Repositorio Académico UPC

Concurrence of adenocarcinoma and large-cell neuroendocrine carcinoma of the stomach is a rare condition. Here, we report a case of gastric collision tumour with large-cell neuroendocrine carcinoma and adenocarcinoma. A 71-year-old Peruvian man presented with nausea, epigastric pain, and weight loss for seven months. An Endoscopic evaluation revealed a huge ulcerative and infiltrative mass in the upper and middle third of the stomach. The patient underwent a D2 total gastrectomy. Microscopically, two separated and attached ulcerative lesions were recognised. The proximal to the cardial lesion showed neuroendocrine morphology and immunoreactivity for synaptophysin, and the other a moderated tubular adenocarcinoma Borrmann type III. Both lesions invaded serosa and lymph nodes metastases were found in 17 of 41 lymph nodes retrieved (one lymph node with neuroendocrine metastatic deposits). Autor(es) :   Payet, Eduardo ;  Pilco, Pau I ;  Montes, Jaime ;  Cordero Morales, ...

Objetivos. Determinar las características del maltrato hacia estudiantes de Medicina de una universidad pública en la provincia de Ica, Perú. Materiales y métodos. Investigación transversal realizada el 2012 en una muestra probabilística de estudiantes de Medicina de primer a sexto año de la Universidad Nacional San Luis Gonzaga. Se elaboró una encuesta con un total de 23 ítems en una escala likert, para medir la percepción de maltrato de tipo psicológico, físico, académico y sexual; se usaron análisis estadísticos univariados y bivariados. Resultados. Se encuestaron 281 estudiantes. La percepción de maltrato psicológico fue 96,8%, académico 86,8%, físico 62,6% y sexual 20,6%; el maltrato físico se incrementó durante el ciclo de estudio clínico-quirúrgico (p=0,001). Los médicos docentes y médicos residentes fueron los principales agresores. Estudiantes hombres reportaron con mayor frecuencia haber recibido tareas como castigo, no recibir los créditos por su trabajo, maltrato fí...

Carta al editor. Autor(es) :   Choque-Chávez, Fernando ;  Huamaní-Fuente, Francisco ;  Canelo Aybar, Carlos Editorial :  Instituto Nacional de Salud (INS) Revista:  Revista Peruana de Medicina Experimental y Salud Pública (Rev Peru Med Exp Salud Publica) Fecha de publicación:  Mar-2016 URL :  http://hdl.handle.net/10757/604538 DOI :  10.17843/rpmesp.2016.331.2020 PDF :  Full Text

Objectives To examine the associations of Intimate partner violence (IPV) with stress-related sleep disturbance (measured using the Ford Insomnia Response to Stress Test [FIRST]) and poor sleep quality (measured using the Pittsburgh Sleep Quality Index [PSQI]) during early pregnancy. Methods This cross-sectional study included 634 pregnant Peruvian women. In-person interviews were conducted in early pregnancy to collect information regarding IPV history, and sleep traits. Adjusted odds ratios (aOR) and 95% confidence intervals (95%CIs) were calculated using logistic regression procedures. Results Lifetime IPV was associated with a 1.54-fold increased odds of stress-related sleep disturbance (95% CI: 1.08–2.17) and a 1.93-fold increased odds of poor sleep quality (95% CI: 1.33–2.81). Compared with women experiencing no IPV during lifetime, the aOR (95% CI) for stress-related sleep disturbance associated with each type of IPV were: physical abuse only 1.24 (95% CI: 0.84–1....

En el presente artículo se explica al lector, la manera en la que el manejo del Impuesto General a las Ventas puede impactar en la liquidez de un proyecto, realizando el cálculo respectivo de las operaciones de la empresa. Editorial:  Gaceta JurÍdica Revista:  Contadores y Empresas Fecha de publicación: Enero 2012 URL:  http://hdl.handle.net/10757/604456 PDF : Full text

Polyomavirus nephropathy is a disease that predominates in renal transplant patients due to the immunosuppressive treatment for the maintenance of the renal graft. The current prevalence of this disease ranges between 1-14%. The suspicion of the disease comes from the presence of decoy cells in urine samples and the gold standard for the diagnosis is the presence of viral inclusions in the renal biopsy. In this case report, we describe a patient with a renal transplant secondary to Takayasu arteritis who presented renal failure evidenced by progressive elevation of serum creatinine. The renal biopsy showed viral inclusions, confirming the diagnosis. Autor(es) :  Godoy Carrillo, María Claudia ;  Meneses Saco, Alejandra ;  Torrealva, C. Víctor ;  Pastor, A. César Editorial :  Universidad Peruana de Ciencias Aplicadas - UPC URL:  http://hdl.handle.net/10757/604547 PDF:  Full Text

Viral metagenomics of feces collected from 58 Peruvian children with unexplained diarrhea revealed several small circular ssDNA genomes. Two genomes related to sequences previously reported in feces from chimpanzees and other mammals and recently named smacoviruses were characterized and then detected by PCR in 1.7 % (1/58) and 19 % (11/58) of diarrheal samples, respectively. Another three genomes from a distinct small circular ssDNA viral group provisionally called pecoviruses encoded Cap and Rep proteins with <35 % identity to those in related genomes reported in human, seal, porcine and dromedary feces. Pecovirus DNA was detected in 15.5 % (9/58), 5.9 % (3/51) and 3 % (3/100) of fecal samples from unexplained diarrhea in Peru, Nicaragua and Chile, respectively. Feces containing these ssDNA genomes also contained known human enteric viral pathogens. The cellular origins of these circular ssDNA viruses, whether human cells, ingested plants, animals or fungal foods, or residents of ...