Repositorio Académico UPC

A recent systematic literature and meta-analysis reported relative efficacy of trimethoprim-sulfamethoxazole (TMP-SMX) for the treatment of toxoplasmic encephalitis (TE) in HIV-infected adults. Here, we estimated relapse rates during secondary prophylaxis with TMP-SMX, and further explored differences in relapse rates prior to introduction of highly active antiretroviral therapy (HAART) and the widespread adoption of HAART... read more AUTOR : Connolly, Mark P. ;  Haitsma, Gertruud ;  Hernández, Adrián V.  ( 0000-0002-9999-4003 )     ;  Vidal, José E. EDITORIAL : Taylor and Francis Ltd. REVISTA: Pathogens and Global Health URL:  http://hdl.handle.net/10757/622484 FULL TEXT:  https://goo.gl/9v8KuR

Objective: The main objective of this study was to detect the presence of 14 respiratory viruses and atypical bacteria (Mycoplasma pneumoniae, Chlamydia pneumoniae), via polymerase chain reaction in patients under 18 years old hospitalized due to community-acquired pneumonia (CAP) from Lima, Peru. Results: Atypical pathogens were detected in 40% (58/146); viral etiologies in 36% (52/146) and coinfections in 19% (27/146). The most common etiological agent was M. pneumoniae (n = 47), followed by C. pneumoniae (n = 11). The most frequent respiratory viruses detected were: respiratory syncytial virus A (n = 35), influenza virus C (n = 21) and parainfluenza virus (n = 10). Viral-bacterial and bacterium-bacterium coinfections were found in 27 cases. In our study population, atypical bacteria (40%) were detected as frequently as respiratory viruses (36%). The presence of M. pneumoniae and C. pneumoniae should not be underestimated as they can be commonly isolated in Peruvian children with CAP...

AUTOR :  Bernabe-Ortiz, Antonio  ( 0000-0002-6834-1376 )     ;   Diez-Canseco, Francisco ;   Vasquez, Alberto ;   Kuper, Hannah ;   Walsham, Matthew ;   Blanchet, Karl EDITORIAL:   British Medical Journal REVISTA:   BMJ Open URL:   http://hdl.handle.net/10757/622480 Full text:   https://goo.gl/vRyysx OBJECTIVE: This study aims to assess the needs of people with disabilities and their level of inclusion in social protection programmes. DESIGN: Population based-survey with a nested case-control study. SETTING: Morropon, a semiurban district located in Piura, northern Peru. PARTICIPANTS: For the population survey, a two-stage sampling method was undertaken using data from the most updated census available and information of each household member aged ≥5 years was collected. In the nested case-control study, only one participant, case or control, per household was included in the study. PRIMARY AND SECONDARY OUTC...

AUTOR :  Castillo Contreras, Ofelia ;   Maguiña Quispe, Jorge ;   Medina Morales, Bryan ;   Malaverry Lozano, Héctor EDITORIAL :  Sociedad Argentina de Gastroenterologia REVISTA:  Acta Gastroenterologica Latinoamericana Existen estudios que encontraron mayor prevalencia de anticuerpos contra Helicobacter pylori (Hp) en gestantes con hiperémesis gravídica, en comparación con mujeres embarazadas asintomáticas. Objetivos. Determinar la relación entre la seropositividad a Hp y la presencia de náusea y vómitos durante las primeras 20 semanas del embarazo en gestantes de una red hospitalaria, entre marzo y diciembre de 2015. Material y métodos. Estudio de casos y controles no pareado en gestantes hasta las 20 semanas de embarazo. El índice de Rhodes para náusea y vómitos clasificó a las gestantes en casos (9-40 puntos) y en controles (8 puntos). La seropositividad a Hp fue definida como IgG ≥ 1,1 U/mL. La asociación entre Hp y náusea y vómitos del emb...

Authors:  Pichilingue-Febres, Alejandra F. ;  Arias-Linares, Miguel A. ;  Araujo-Castillo, Roger V. Journal:  Breast Cancer Research and Treatment We would like to express our opinion regarding a Parise and Caggiano paper recently published in your journal. We certainly believe this is a great contribution, since it found that node-negative HER2 (+) breast cancer patients have better survival contrary to the common knowledge. This finding could reflect the consequences of targeted therapies that are changing the natural history of the disease. However, we think that such an interesting analysis could also have been done with stage III and IV patients, since this group of people could benefit greatly from these findings. In fact, new guidelines now recommend the use of HER2-specific therapy for stage IV patients with positive markers, even for life if they do not show signs of progression. Additionally, we would like to discuss the value of adding the Ki-67 marker to ...